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This course will be focused on the understanding scientific and metallurgical principles used for material processing and fabrication, microstructural control, composition adjustment, mechanical and metallurgical property evaluation, and development of structure-property correlation for advanced structural materials (with emphasis on metallic materials). The goal of this course is to achieve that senior and graduate students are able to select and design structural materials with superior properties as strength members used in advanced engineering systems. The materials topics intended to cover in this course will include phase diagram and microstructural control, hardening of structural materials, conventional and nanostructured steels with high strength, bulk metallic glasses (BMGs): Glass forming ability, atomic structures and mechanical properties, high-temperature superalloys, structural-gradient metallic materials, high-temperature refractory metals and alloys, and light-weight Ti-based alloys (including two-phase TiAl intermetallic alloys).